health

ai-companion-robot-helps-some-seniors-fight-loneliness,-but-others-hate-it

AI companion robot helps some seniors fight loneliness, but others hate it

AI buddy —

There’s limited evidence for health benefits so far; early work suggests no one-size-fits-all.

ElliQ, an AI companion robot from Intuition Robotics.

Enlarge / ElliQ, an AI companion robot from Intuition Robotics.

Some seniors in New York are successfully combating their loneliness with an AI-powered companion robot named ElliQ—while others called the “proactive” device a nag and joked about taking an ax to it.

The home assistant robot, made by Israel-based Intuition Robotics, is offered to New York seniors through a special program through the state’s Office for the Aging (NYSOFA). Over the past year, NYSOFA has partnered with Intuition Robotics to bring ElliQ to over 800 seniors struggling with loneliness. In a report last week, officials said they had given out hundreds and had only 150 available devices.

ElliQ includes a tablet and a two-piece lamp-like robot with a head that lights up and rotates to face a speaker. Marketed as powered by “Cognitive AI technology,” it proactively engages in conversations with users, giving them reminders and prompts, such as asking them how they’re doing, telling them it’s time to check their blood pressure or take their medicine, and asking if they want to have a video call with family. Speaking with a female voice, the robot is designed to hold human-like conversations, engage in small talk, express empathy, and share humor. It can provide learning and wellness programs, such as audiobooks and relaxation exercises.

Interest in using social robots, such as ElliQ, for elder care has been growing for years, but the field still lacks solid evidence that the devices can significantly improve health, well-being, and depression. Systemic reviews in 2018 found the technology had potential, but studies lacked statistical significance and rigorous design.

The program in New York adds to the buzz but doesn’t offer the high-quality study design that could yield definitive answers. In August, the state released a report on an unspecified number of ElliQ users, which indicated that the device was helpful. Specifically, 59 percent of users reported the device was “very helpful” at reducing loneliness, while 37 percent reported it was “helpful” and only 4 percent reported it as “unhelpful.” Engagement with the device declined over time, with users initially interacting with ElliQ an average of 62 times a day in the first 15 days of use, which fell to 21 times a day between 60 and 90 days and 33 times a day after 180.

Mixed feelings

“We had high hopes for the efficacy of ElliQ, but the results that we’re seeing are truly exceeding our expectations,” Greg Olsen, director of the New York State Office for the Aging, said in a statement at the time of the report’s release. “The data speaks for itself, and the stories that we’re hearing from case managers and clients around the state have been nothing short of unbelievable.”

But other recent data on the potential for companion robots to reduce loneliness has indicated that there’s no one-size-fits-all approach. There are a lot of factors that can influence how individuals perceive such a device. A 2021 qualitative study evaluated the responses from 16 seniors who were asked for feedback on three types of robot companions, including ElliQ. The results were mixed for the proactive robot. While some felt the occasional chattiness of ElliQ would be comforting during an otherwise solitary day, others felt it was intrusive and “nagging.” Some felt the device’s tone was “rude.”

“I don’t know whether that would drive me mental if it kept interrupting me and telling me what to do … I might want to get an ax and cut it up,” one study participant said.

How welcoming a person might be to an assertive AI-assistant like ElliQ may link with a person’s general preferences regarding human company, the authors suggested. Those who value their space and autonomy may be less open to such as device compared with more gregarious seniors.

While some participants said ElliQ’s reminders could be useful, others expressed a deep concern that an overreliance on technology for everyday tasks—like paying bills, taking medications, or turning lights off—could hasten the decline of cognitive and physical abilities. Study participants also raised concerns regarding the inauthenticity of a relationship with a nonhuman, a loss of dignity, and a lack of control. Some disliked that ElliQ couldn’t be fully controlled by the user and was so assertive, which some perceived as pushy. Some worried about feeling embarrassed about being seen interacting with a robot companion. A 2022 study also explored the issue of stigma, with participants expressing that the use of such devices could reinforce stereotypes of aging, including isolation and dependency.

While researchers continue to explore the potential use and design of AI-powered companion robots, anecdotes from New York’s program suggest the tools are clearly helpful for some. One New Yorker named Priscilla told CBS News she found ElliQ helpful.

“She keeps me company. I get depressed real easy. She’s always there. I don’t care what time of day, if I just need somebody to talk to me,” Priscilla said. “I think I said that’s the biggest thing, to hear another voice when you’re lonely.”

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FDA approves first CRISPR therapy—here’s how it works against sickle cell

historic —

The landmark treatment turns on another blood protein that prevents sickling.

This digitally colorized scanning electron micrograph (SEM) revealed some of the comparative ultrastructural morphology between normal red blood cells (RBCs), and a sickle cell RBC (left) found in a blood specimen of an 18-year-old female patient with sickle cell anemia.

Enlarge / This digitally colorized scanning electron micrograph (SEM) revealed some of the comparative ultrastructural morphology between normal red blood cells (RBCs), and a sickle cell RBC (left) found in a blood specimen of an 18-year-old female patient with sickle cell anemia.

The Food and Drug Administration on Friday approved two gene therapies to treat sickle cell disease, one of the which is the first CRISPR/Cas9-based treatment to win regulatory approval in the US.

The announcement is a landmark in the treatment of sickle cell disease, a devastating condition in which red blood cells deform into a sickle shape and clog up blood vessels. Sickle cell disease affects around 100,000 people in the US, most commonly African Americans. It leads to anemia, vaso-occlusive events and crises (painful episodes in which small blockages starve tissue of oxygen), strokes, progressive and irreversible organ damage, decreased quality of life, and early death.

Until today, treatments have been limited. A bone marrow transplant from a genetically matched sibling can cure the condition more than 90 percent of the time, but only around 20 percent of people with the disease have such a genetically matched sibling donor. There are also multiple drugs available and supportive care, but these mainly reduce the severity of the disease. The new gene therapy treatments, on the other hand, have shown to be highly effective at preventing vaso-occlusive events and crises.

“Sickle cell disease is a rare, debilitating and life-threatening blood disorder with significant unmet need, and we are excited to advance the field, especially for individuals whose lives have been severely disrupted by the disease, by approving two cell-based gene therapies today,” said Nicole Verdun, director of the Office of Therapeutic Products within the FDA’s Center for Biologics Evaluation and Research, said in the FDA’s announcement.

To understand how the gene therapies work, it’s useful to understand what causes sickle cell disease. The central problem is with adult hemoglobin, the iron-containing protein in red blood cells that transports oxygen from the lungs to the rest of the body. In patients with sickle cell disease, there’s a single, small mutation in the gene that encodes hemoglobin. The mutation is a switch of a single nucleotide, or base, (often represented by letters A, C, T, and G). The switch of an A to a T in the genetic code for hemoglobin results in a hemoglobin protein with a valine instead of a glutamic acid at the sixth amino acid position. This transforms normal adult hemoglobin (HbA) to sickle hemoglobin (HbS). In red blood cells, when HbS loses the oxygen it was carrying, it polymerizes with itself, forming strand-like structures that deform the cell.

Effective edits

The CRISPR/Cas9 therapy approved today, called Casgevy, prevents this deformation by essentially turning on the production of another type of hemoglobin encoded in our genetic blueprints—fetal hemoglobin (HbF). HbF is optimized for pregnancy, transferring oxygen from maternal blood to fetal tissue, and the gene that encodes it is shut off shortly after birth as the body transitions to HbA. About six months after birth, HbF usually makes up just 1 percent to 2 percent of hemoglobin in the body.

But, HbF can effectively treat sickle cell disease—the hemoglobin transports oxygen just fine in adults, and it doesn’t polymerize. Moreover, when it’s mixed with HbS, it gets in the way of the mutated protein polymerizing with itself, preventing it from forming structures that deform red blood cells.

Casgevy turns on HbF with the CRISPR/Cas9 system, a gene-editing system initially swiped from bacteria that snips DNA using an enzyme (a nuclease) called Cas9. Cas9 can be targeted to specific stretches of DNA using a short RNA guide sequence. In Casgevy, the CRISPR/Cas9 system is targeted to snip a gene encoding a protein called BCL11A, which controls other genes, aka a transcription factor. The BCL11A transcription factor is the protein responsible for shutting off the gene for HbF shortly after birth as the body transitions to the adult version. With the CRISPR/Cas9 snip, BCL11A is shut off, and HbF production can resume.

For patients being treated, this process involves first harvesting their bone marrow stem cells, which then get CRISPR-ed in a specialized lab. Meanwhile, the patients receive chemotherapy to kill bone marrow cells to make way for the gene-edited cells that are then put back in. Of 31 patients treated with Cagevy and followed for at least 24 months, 29 (93.5 percent) went at least 12 consecutive months without a vaso-occlusive crisis.

The other gene therapy approved by the FDA today is Lyfgenia, which used a Lentiviral vector to insert genes into the human genome. In this case, the system delivers the genetic code for a modified type of hemoglobin that is designed to be anti-sickling, called HbAT87Q. Among 32 patients treated with Lyfgenia, 28 (88 percent) were free of vaso-occlusive events for between six to 18 months after treatment.

Both gene therapies are approved for patients ages 12 years and up.

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get-your-groove-on-with-these-10-fun-online-dance-classes

Get Your Groove On With These 10 Fun Online Dance Classes

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12-exercises-you-can-perform-at-your-standing-desk

12 Exercises You Can Perform at Your Standing Desk

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how-active-games-can-make-you-healthy

How Active Games Can Make You Healthy

 

Video games have been blamed for sedentary lifestyles and social problems since early arcade games hit the streets in the 1970s. Throughout my career, from post-doctoral research to the company boardroom, I have made it my mission to change that perception and truly bring physical activity into the gaming industry.

The recipe is simple: By fully utilizing the capabilities of mixed reality technologies, we can make active, social, and fun gaming experiences that reward exercise. Combining the benefits of an active lifestyle with everything we love about video games, we can finally bury all the negative stereotypes for good.

The Pandemic Glued Us to the Couch

The COVID-19 pandemic was a tough time for many. A study by WHO found that the global prevalence of anxiety and depression increased by 25%. Especially young people found themselves cut off from their social networks. At the same time, interest in gaming skyrocketed.

When we were stuck in our houses, playing video games became one of few ways to spend time with friends and family. Studies undertaken after the pandemic show that people who played augmented reality games like Pokémon Go or Harry Potter: Wizards Unite were less likely to develop anxiety and depression. Another study showed that young people who played online games coped better with anxiety, depression, and stress related to lockdown measures.

Many of our gaming habits have stuck with us after restrictions were lifted. In the US, 56% of male and 47% of female respondents to a recent survey said they play video games as often as they did during the pandemic. Safe to say, gaming is here to stay.

Active Games Make People Active

While games are more popular than ever, we are facing another problem: Sitting down is the new pandemic. As much as 80% of the global underage population does not get enough weekly exercise. The average American sits more than 6.5 hours daily, and it’s even worse in the UK at over 9 hours. Yet we have to acknowledge that going for a run or to the gym is not for everyone. To include more people, we have to rethink what exercise could be.

Gamified exercise is the key. Active games have been around for a long time and are growing in popularity. The first dancing game with a floor pad launched in 1987, and by the late 90s, they were a feature at every arcade. All major consoles have featured active games since Playstation 2’s EyeToy. Yet, these games all share the same issue: they are primarily for one or two players, and the experience relies heavily on factors like additional controllers, having a good TV, or enough space in the living room.

Pokémon Go took on this challenge and made active gaming accessible. Players have to move around to progress and so they had no other choice than to take the dog for a walk or go to the park. Data from 2017 showed the number of active players that walked more than 10,000 steps per day had increased from 15% to 28% since the game launched. Using AR technology and mobile phones, inserting the game directly into the player’s surroundings made the gaming experience feel real.

So how do we build on the success of Pokémon Go? For me, the digitalization of theme parks, arcades, and activity centers, provides a fantastic opportunity to introduce MR active games to larger groups. Using immersive technology, we can create fun and challenging group gaming experiences that could never fit in our living rooms.

Active Games Are Social Arenas

Video games are social, and creating social games is also what MR systems do best. New, immersive, digital attractions are a great social way to inspire competition and get people moving. Friends can work out together, and you are free to move around in the game arena. Competing against real people in a mixed reality space where they can see, hear, touch, and talk to each other while playing takes the gaming experience to the next level.

As a social arena, gearless MR games have an advantage over their equipment-based VR cousins. By removing the need for mobile phones or headwear, we can create games that let you stay connected with your fellow players in the real world. The game truly becomes a challenge you face together. The sense of jeopardy is real, as are the interactions you have with other players.

MR technology also lets us create new, gamified activities for traditional sports venues such as gyms or climbing centers. By boosting the spread of MR gaming experiences, we can introduce healthy activity to more people and promote healthy living. I can think of no better use of technology.

Guest Post


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vitruvian’s-trainer+-is-the-next-generation-home-gym

Vitruvian’s Trainer+ Is the Next-Generation Home Gym

March 3, 2022 by

Thousands experienced the newest technological advance in fitness, the Vitruvian Trainer+, which debuted at CES 2022 last week. Recently featured on FORBES.COM and named one of the best fitness workout equipment for your compact, space-saving home gym, The Trainer+ is the most powerful adaptive fitness device coming to the market, with cutting-edge algorithmic technology for the most intelligent workout.

The Trainer+ is a highly portable, luxurious, and sleek carbon fiber platform that employs algorithms, a dynamic tension system, and has the power to release up to a whopping 440lb, smashing its competition in weight training capabilities. Featuring intelligent software that motivates, responds, and adapts to you, you have a whole gym at your fingertips. When paired with the Vitruvian App, the compact Trainer+ knows how much weight you can safely and effectively move at any given time. The app offers coached sessions with leading trainers, customizable workout plans, performance data insights, over 200+ exercises available, technique tutorials, and the ability to compete with friends.  

The innovative platform was developed more than a decade ago by Jon Gregory, a former high-frequency trader with a degree in applied physics after he began looking for an alternative to pumping metal weights in between trades at his desk. He decided to combine his two passions and create algorithms that revolutionize how we work out.  How does the Trainer+ work? Essentially, the adaptive weight acts as a spotter, learning the user’s ability to lift, adjusting to their strengths and weaknesses over 50 times per second.

Once the Trainer+ builds a data-driven picture of your training level, it can modify the workouts accordingly to extract the best out of your efforts and increase your strength rather than maintain it. What sets the Trainer+ apart is its ability to simultaneously offer concentric and eccentric resistance workouts.

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Last modified: March 2, 2022

About the Author:

Tom is the Editorial Director at TheCESBible.com

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Caregiver Smart Solutions wins AARP’s best Eureka Park startup to help those 50+ to Age in Place with technologies focused on making homes smarter, safer, accessible, and fun!

January 15, 2022 by

Caregiver Smart Solutions is The Best Way to Monitor Loved Ones As they Age In Place. By using AI for Aging in Place, we provide a proactive solution that enables your loved ones to retain their independence, dignity, and live on their own as long as possible while reducing your stress through Peace of Mind.

This was confirmed at CES 2022. It all started by winning the CTA Foundation Eureka Park Accessibility Contest. Then we won the International Business Times for Best of CES 2022. Then finally Caregiver Smart Solutions wins AARP’s best Eureka Park startup to help those 50+ to Age in Place with technologies focused on making homes smarter, safer, accessible, and fun!

We are helping our loved ones be able to live their “Golden Years” at home. At the same time, our system allows us – their adult children – to truly answer the critical question. – “How are they doing?” The insight we provide is stress-reducing, life-changing, and gives us so much incredible information!

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Last modified: January 12, 2022

About the Author:

Tom is the Editorial Director at TheCESBible.com

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yogifi-for-her-well-organized-yoga-mat

YogiFi for HER Well-organized Yoga Mat

October 28, 2021 by

What is she keeping right here?

Put up-pandemic lifestyles has accelerated the “hybrid fitness” model—an diagram to exercise that meets the fresh demands of a fresh each day life blurring the traces between dwelling and work. Fitness giants, cherish Orange Thought and Soul Cycle, luxuriate in created merchandise to meet this hybrid model, similar to keeping digital offerings or the Soul Cycle At-Home Bike, but I desired to introduce you to a fresh player in the industry with a recurring secure on hybrid fitness.

YogiFi is the first tidy yoga mat in the marketplace, geared up with a built-in modern sensor layer to note and supply recommendations to lend a hand factual develop in true-time. The YogiFi mat’s AI affords the in-studio feel to raise at-dwelling yoga note AND instructors are ready to sync their mats with their students to note their growth and continue their industrial, without reference to the device.

Why is she so pleased?

Because she has learned her final wellness partner and also, we requested her smartly!

Product Highlights:

— AI-Powered Yoga Mat (Bluetooth + WiFi Enabled)

— Precise-Time Feedback from Digital Coach

— Customized Exercise Plans

— Tune Flexibility, Energy, Steadiness & Yoga abilities

— Digital Ambiance to carry nature shut to dwelling

How did it initiate?

Founded in 2016 and launched in 2020, Founder Murali Somisetty used to be impressed to impact YogiFi after yoga had cured his chronic debilitating support danger. After practicing as an licensed yoga trainer, he realized individuals were inconsistent in attending courses, due to busy work schedules, family commitments, etc. So, he idea, “what if a yoga mat might well well well additionally talk over with you and e book you step-by-step cherish a yoga trainer? What if we might well well well additionally program the mat to learn different postures the utilization of AI?” Thus, the birth of YogiFi.

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Final modified: October 28, 2021

In regards to the Creator:

Eric is the Editor-In-Chief at TheCESBible.com

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