health

with-over-900-us-measles-cases-so-far-this-year,-things-are-looking-bleak

With over 900 US measles cases so far this year, things are looking bleak

CDC, elimination, health, measles, MMR, vaccination / /

As of Friday, April 25, the US has confirmed over 900 measles cases since the start of the year. The cases are across 29 states, but most are in or near Texas, where a massive outbreak continues to mushroom in close-knit, undervaccinated communities.

On April 24, the Centers for Disease Control and Prevention had tallied 884 cases across the country. Today, the Texas health department updated its outbreak total, adding 22 cases to its last count from Tuesday. That brings the national total to at least 906 confirmed cases. Most of the cases are in unvaccinated children and teens.

Overall, Texas has identified 664 cases since late January. Of those, 64 patients have been hospitalized, and two unvaccinated school-aged children with no underlying medical conditions have died of the disease. An unvaccinated adult in New Mexico also died from the infection, bringing this year’s measles death toll to three.

The cases and deaths are breaking records. In the past 30 years, the only year with more measles cases than the current tally was 2019, which saw 1,274 cases. Most of those cases were linked to large, extended outbreaks in New York City that took 11 months to quell. The US was just weeks away from losing its elimination status, an achievement earned in 2000 when the country first went 12 months without continuous transmission.

Since 2019, vaccination coverage of the measles, mumps, and rubella (MMR) vaccine among US kindergartners has only fallen. National rates fell from 95 percent in 2019—the threshold considered necessary to keep measles from spreading—to 92.7 percent in the 2023–24 school year, the most recent year for which there’s data.

On the brink

In 2019, amid the record annual case tally, cases had only reached a total of 704 by April 26. With this year’s tally already over 900, the country is on track to record a new high. Before 2019, the next highest case total for measles was in 1994. That year, the country saw 899 cases, which 2025 has already surpassed.

With over 900 US measles cases so far this year, things are looking bleak Read More »

tapeworm-in-fox-poop-that-will-slowly-destroy-your-organs-is-on-the-rise

Tapeworm in fox poop that will slowly destroy your organs is on the rise

health, Infectious disease, parasites, tapeworm / /

No matter how bad things might seem, at least you haven’t accidentally eaten fox poop and developed an insidious tapeworm infection that masquerades as a cancerous liver tumor while it slowly destroys your organs and eventually kills you—or, you probably haven’t done that.

What’s more, according to a newly published study in Emerging Infectious Diseases, even if you have somehow feasted on fox feces and acquired this nightmare parasite, it’s looking less likely that doctors will need to hack out chunks of your organs to try to stop it.

That’s the good news from the new study. The bad news is that, while this infection is fairly rare, it appears to be increasing. And, if you do get it, you might have a shorter lifespan than the uninfected and may be sicker in general.

Meet the fox tapeworm

The new study is a retrospective one, in which a group of doctors in Switzerland examined medical records of 334 patients who developed the disease alveolar echinococcosis (AE) over a 50-year span (1973–2022). AE is an understudied, life-threatening infection caused by the fox tapeworm, Echinococcus multilocularis. The parasite is not common, but can be found throughout the Northern Hemisphere, particularly regions of China and Russia, and countries in continental Europe and North America.

In the parasite’s intended lifecycle, adult intestinal worms release eggs into the feces of their primary host—foxes, or sometimes coyotes, dogs, or other canids. The eggs then get ingested by an intermediate host, such as voles. There, eggs develop into a spherical embryo with six hooks that pierce through the intestinal wall to migrate to the animal’s organs, primarily the liver. Once nestled into an organ, the parasites develop into multi-chambered, thin-walled cysts—a proliferative life stage that lasts indefinitely. As more cysts develop, the mass looks and acts like cancer, forming necrotic cavities and sometimes metastasizing to other organs, such as the lungs and brain. The parasite remains in these cancerous-like masses, waiting for a fox to eat the cyst-riddled organs of its host. Back in a fox, the worms attach to the intestines and grow into adults.

Tapeworm in fox poop that will slowly destroy your organs is on the rise Read More »

drunk-man-walks-into-climate-change,-burns-the-bottoms-of-his-feet-off

Drunk man walks into climate change, burns the bottoms of his feet off

asphalt, burns, climate change, health, Science / /

In the burn unit, doctors gave the man a pain reliever, cleaned the burns, treated them with a topical antibiotic, and gave them an antimicrobial foam dressing. At a follow-up appointment, the wounds appeared to be healing without complications.

While the man recovered from the injury, the author of the case study—Jeremy Hess, an expert in emergency medicine and global environmental health at the University of Washington—warned that the risk of such injuries will only grow as climate change continues.

“Extreme heat events increase the risk of contact burns from hot surfaces in the environment,” he wrote. “Young children, older adults, unhoused persons, and persons with substance use disorder are at elevated risk for these types of burns.”

Last year, The New York Times reported that burn centers in the southwest have already begun seeing larger numbers of burns from contact with sidewalks and asphalt during heat waves. In some cases, the burns can turn fatal if people lose consciousness on hot surfaces—for instance, from overdoses, heat stroke, intoxication, or other health conditions. “Your body just literally sits there and cooks,” Clifford Sheckter, surgeon and a burn prevention researcher at Stanford University, told the Times last year. “When somebody finally finds you, you’re already in multisystem organ failure.”

Drunk man walks into climate change, burns the bottoms of his feet off Read More »

controversial-doc-gets-measles-while-treating-unvaccinated-kids—keeps-working

Controversial doc gets measles while treating unvaccinated kids—keeps working

anti-vaccine, CDC, children's health defense, health, measles, outbreak, robert f kennedy jr / /

In the video with Edwards that has just come to light, CHD once again uses the situation to disparage MMR vaccines. Someone off camera asks Edwards if he had never had measles before, to which he replies that he had gotten an MMR vaccine as a kid, though he didn’t know if he had gotten one or the recommended two doses.

“That doesn’t work then, does it?” the off-camera person asks, referring to the MMR vaccine. “No, apparently not, ” Edwards replies. “Just wear[s] off.”

It appears Edwards had a breakthrough infection, which is rare, but it does occur. They’re more common in people who have only gotten one dose, which is possibly the case for Edwards.

A single dose of MMR is 93 percent effective against measles, and two doses are 97 percent effective. In either case, the protection is considered lifelong.

While up to 97 percent effectiveness is extremely protective, some people do not mount protective responses and are still vulnerable to an infection upon exposure. However, their illnesses will likely be milder than if they had not been vaccinated. In the video, Edwards described his illness as a “mild case.”

The data on the outbreak demonstrates the effectiveness of vaccination. As of April 18, Texas health officials have identified 597 measles cases, leading to 62 hospitalizations and two deaths in school-aged, unvaccinated children with no underlying medical conditions. Most of the cases have been in unvaccinated children. Of the 597 cases, 12 (2 percent) had received two MMR doses previously, and 10 (1.6 percent) had received one dose. The remaining 96 percent of cases are either unvaccinated or have no record of vaccination.

Toward the end of the video, Edwards tells CHD he’s “doing what any doctor should be doing.”

Controversial doc gets measles while treating unvaccinated kids—keeps working Read More »

“lab-leak”-marketing-page-replaces-federal-hub-for-covid-resources

“Lab leak” marketing page replaces federal hub for COVID resources

CDC, COVID-19, health, Lab leak, SARS-CoV-2, Trump / /

After obliterating the federal office on long COVID and clawing back billions in COVID funding from state health departments, the Trump administration has now entirely erased the online hub for federal COVID-19 resources. In its place now stands a site promoting the unproven idea that the pandemic virus SARS-CoV-2 was generated in and leaked from a lab in China, sparking the global health crisis.

Navigating to COVID.gov brings up a slick site with rich content that lays out arguments and allegations supporting a lab-based origin of the pandemic and subsequent cover-up by US health officials and Democrats.

Previously, the site provided unembellished quick references to COVID-19 resources, including links to information on vaccines, testing, treatments, and long COVID. It also provided a link to resources for addressing COVID-19 vaccine misconceptions and confronting misinformation. That all appears to be gone now, though some of the same information still remains on a separate COVID-19 page hosted by the Centers for Disease Control and Prevention.

While there remains no definitive answer on how the COVID-19 pandemic began, the scientific data available on the topic points to a spillover event from a live wild animal market in Wuhan, China. The scientific community largely sees this as the most likely scenario, given the data so far and knowledge of how previous outbreak viruses originated, including SARS-CoV-1. By contrast, the lab origin hypothesis largely relies on the proximity of a research lab to the first cases, conjecture, and distrust of the Chinese government, which has not been forthcoming with information on the early days of the health crisis. Overall, the question of SARS-CoV-2’s origin has become extremely politicized, as have most other aspects of the pandemic.

“Lab leak” marketing page replaces federal hub for COVID resources Read More »

trump-admin-accused-of-censoring-nih’s-top-expert-on-ultra-processed-foods

Trump admin accused of censoring NIH’s top expert on ultra-processed foods

addiction, censorship, food, health, kevin hall, NIH, research, Science, ultra processed foods / /

Hall claims that because of this, aides for Kennedy blocked him from being directly interviewed by New York Times reporters about the study. Instead, Hall was allowed to provide only written responses to the newspaper. However, Hall claims that Andrew Nixon, a spokesperson for Kennedy, then downplayed the study’s results to the Times and edited Hall’s written responses and sent them to the reporter without Hall’s consent.

Further, Hall claims he was barred from presenting his research on ultra-processed foods at a conference and was forced to either edit a manuscript he had worked on with outside researchers or remove himself as a co-author.

An HHS spokesperson denied to CBS that Hall was censored or that his written responses to the Times were edited. “Any attempt to paint this as censorship is a deliberate distortion of the facts,” a statement from the HHS said.

In response, Hall wrote to CBS, “I wonder how they define censorship?”

Hall said he had reached out to NIH leadership about his concerns in hopes it all was an “aberration” but never received a response.

“Without any reassurance there wouldn’t be continued censorship or meddling in our research, I felt compelled to accept early retirement to preserve health insurance for my family,” he wrote in the LinkedIn post. “Due to very tight deadlines to make this decision, I don’t yet have plans for my future career.”

Trump admin accused of censoring NIH’s top expert on ultra-processed foods Read More »

cdc-struggling-to-fight-raging-measles-outbreak-after-deep-funding,-staff-cuts

CDC struggling to fight raging measles outbreak after deep funding, staff cuts

ACIP, CDC, health, measles, MMR, outbreak, vaccination / /

In now-rarified comments from experts at the Centers for Disease Control and Prevention, an agency official on Tuesday evening said the explosive measles outbreak mushrooming out of West Texas will require “significant financial resources” to control and that the agency is already struggling to keep up.

“We are scrapping to find the resources and personnel needed to provide support to Texas and other jurisdictions,” said David Sugerman, the CDC’s lead on its measles team. The agency has been devastated by brutal cuts to CDC staff and funding, including a clawback of more than $11 billion in public health funds that largely went to state health departments.

Sugerman noted that the response to measles outbreaks is generally expensive. “The estimates are that each measles case can be $30,000 to $50,000 for public health response work—and that adds up quite quickly.” The costs go to various responses, including on-the-ground response teams, vaccine doses and vaccination clinics, case reporting, contact tracing, mitigation plans, infection prevention, data systems, and other technical assistance to state health departments.

In the past, the CDC would provide media briefings and other public comments on the responses to such an extraordinarily large and fast-moving outbreak. However, Sugerman’s comments are among the first publicly made by CDC experts under the current administration. He spoke about the outbreak at the very end of an all-day public meeting of the agency’s Advisory Committee on Immunization Practices (ACIP), which discussed a broad range of vaccine and vaccine-preventable diseases over the course of the day.

The meeting was initially planned for February but was abruptly canceled and then rescheduled upon the Trump administration coming into office, including the new health secretary and longtime anti-vaccine advocate, Robert F. Kennedy, Jr. But, despite concern for ACIP’s future, the meeting proceeded more or less as usual on Tuesday and continues today with additional topics. The last 30 minutes of yesterday’s agenda was set aside for an update on the measles outbreak.

“I find it absolutely devastating that we’re having this update today,” ACIP chair Keipp Talbot said at the outset of Sugerman’s update. “There’s no reason why we have healthy children dying of measles in the US when this vaccine is amazing,” Talbot said, referencing the measles, mumps, and rubella (MMR) vaccine. “It’s highly effective and has very long-lasting immunity.” Two doses of MMR offer 97 percent protection against the virus, which is among the most infectious viruses known.

CDC struggling to fight raging measles outbreak after deep funding, staff cuts Read More »

autism-rate-rises-slightly;-rfk-jr.-claims-he’ll-“have-answers-by-september“

Autism rate rises slightly; RFK Jr. claims he’ll “have answers by September“

autism, CDC, health, robert f kennedy jr, Testing / /

Among the sites, there were large differences. Prevalence ranged from 9.7 per 1,000 children who were 8 years old in Texas (Laredo) to 53.1 in California. These differences are likely due to “differences in availability of services for early detection and evaluation and diagnostic practices,” the CDC and network researchers wrote.

For instance, California—the site with the highest prevalence among 8-year-olds and also 4-year-olds—has a local initiative called the Get SET Early model. “As part of the initiative, hundreds of local pediatricians have been trained to screen and refer children for assessment as early as possible, which could result in higher identification of ASD, especially at early ages,” the authors write. “In addition, California has regional centers throughout the state that provide evaluations and service coordination for persons with disabilities and their families.”

On the other hand, the low ASD rates at the network’s two Texas sites could “suggest lack of access or barriers to accessing identification services,” the authors say. The two Texas sites included primarily Hispanic and lower-income communities.

The newly revealed higher rates in some of the network’s underserved communities could link ASD prevalence to social determinants of health, such as low income and housing and food insecurity, the authors say. Other factors, such as higher rates of preterm birth, which is linked to neurodevelopmental disabilities, as well as lead poisoning and traumatic brain injuries, may also contribute to disparities.

Anti-vaccine voices

The detailed, data-heavy report stands in contrast to the position of health secretary Robert F. Kennedy Jr., a longtime anti-vaccine advocate who promotes the false and thoroughly debunked claim that autism is caused by vaccines. Last month, Kennedy hired the discredited anti-vaccine advocate David Geier to lead a federal study examining whether vaccines cause autism, despite numerous high-quality studies already finding no link between the two.

Geier, who has no medical or scientific background, has long worked with his father, Mark Geier, to promote the idea that vaccines cause autism. In 2011, Mark Geier was stripped of his medical license for allegedly mistreating children with autism, and David Geier was fined for practicing medicine without a license.

In a media statement Tuesday in response to the new report, Kennedy called autism an “epidemic” that is “running rampant.” He appeared to reference his planned study with Geier, saying: “We are assembling teams of world-class scientists to focus research on the origins of the epidemic, and we expect to begin to have answers by September.”

Autism rate rises slightly; RFK Jr. claims he’ll “have answers by September“ Read More »

ct-scans-could-cause-5%-of-cancers,-study-finds;-experts-note-uncertainty

CT scans could cause 5% of cancers, study finds; experts note uncertainty

CT scans, health / /

Uncertainty and balancing

“The estimates, while based on the best models available to the authors, are indirect, so there is considerable uncertainty about the estimates,” Stephen Duffy, emeritus professor of Cancer Screening at Queen Mary University of London, said in a statement. “Thus, I would say to patients that if you are recommended to have a CT scan, it would be wise to do so.”

Duffy also highlighted that in the context of a person’s overall risk of cancer, CT scans don’t move the needle much. There were a little over 100,000 cancers linked to 93 million scans. “This amounts to around a 0.1 percent increase in cancer risk over the patient’s lifetime per CT examination,” he said. The lifetime risk of cancer in the US population is around 40 percent. Thus, the additional risk from CT scans “is small.” Overall, when a CT scan is deemed necessary, the “likely benefit in diagnosis and subsequent treatment of disease outweighs the very small increase in cancer risk.”

Doreen Lau, a cancer biology expert at Brunel University of London, agreed: “The findings don’t mean that people should avoid CT scans when recommended by a doctor. In most cases, the benefit of detecting or ruling out serious illness far outweighs the very small risk of harm.”

Still, the rise in CT scans in recent years may suggest that doctors could cut back on their use. In an accompanying editorial, Ilana Richman of Yale University and Mitchell Katz of NYC Health and Hospitals discussed ways that doctors could make sure they’re balancing risks and benefits before using CT scans, including using diagnostic algorithms and offering alternative imaging options, such as ultrasounds and magnetic resonance imaging (MRIs).

“As with all complex problems, there will be no simple solution,” they write. But, “educating clinicians about avoiding low-value testing and, in circumstances where alternatives are readily available, involving patients in the decision to do a CT scan may help shift culture and practice.”

CT scans could cause 5% of cancers, study finds; experts note uncertainty Read More »

experimental-drug-looks-to-be-gastric-bypass-surgery-in-pill-form

Experimental drug looks to be gastric bypass surgery in pill form

GLP-1, health, obesity, Ozempic, syndication, weight loss / /

In rats, the drug produced a consistent 1 percent weekly weight loss over a six-week study period while preserving 100 percent of lean muscle mass.

In a first-in-human pilot study of nine participants, the drug was safe with no adverse effects. Tissue samples taken from the intestine were used to confirm that the coating formed and was also cleared from the body within 24 hours. The study wasn’t designed to assess weight loss, but blood testing showed that after the drug was given, glucose levels and the “hunger hormone” ghrelin were lower while the levels of leptin, an appetite-regulating hormone, were higher.

“When nutrients are redirected to later in the intestine, you’re activating pathways that lead towards satiety, energy expenditure, and overall healthy, sustainable weight loss,” Dhanda says.

Syntis Bio’s findings in animals also hint at the drug’s potential for weight loss without compromising muscle mass, one of the concerns with current GLP-1 drugs. While weight loss in general is associated with numerous health benefits, there’s growing evidence that the kind of drastic weight loss that GLP-1s induce can also lead to a loss of lean muscle mass.

Louis Aronne, an obesity medicine specialist and professor of metabolic research at Weill-Cornell Medical College, says that while GLP-1s are wildly popular, they may not be right for everyone. He predicts that in the not-so-distant future there will be many drugs for obesity, and treatment will be more personalized. “I think Syntis’ compound fits in perfectly as a treatment that could be used early on. It’s a kind of thing you could use as a first-line medication,” he says. Arrone serves as a clinical adviser to the company.

Vladimir Kushnir, professor of medicine and director of bariatric endoscopy at Washington University in St. Louis, who isn’t involved with Syntis, says the early pilot data is encouraging, but it’s hard to draw any conclusions from such a small study. He expects that the drug will make people feel fuller but could also have some of the same side effects as gastric bypass surgery. “My anticipation is that this is going to have some digestive side effects like bloating and abdominal cramping, as well as potentially some diarrhea and nausea once it gets into a bigger study,” he says.

It’s early days for this novel technique, but if it proves effective, it could one day be an alternative or add-on drug to GLP-1 medications.

This story originally appeared on wired.com.

Experimental drug looks to be gastric bypass surgery in pill form Read More »

holy-water-brimming-with-cholera-compels-illness-cluster-in-europe

Holy water brimming with cholera compels illness cluster in Europe

Cholera, ECDC, health, holy water, Infectious disease, water / /

“As the infectious dose of V. cholerae O1 has been estimated to be 105–108 [100,000 to 100 million] colony-forming units (CFU), this suggests the holy water was heavily contaminated and bacteria remained viable at ambient temperature during the flight and in Europe,” the German and UK researchers who authored the report wrote.

Global plague

Testing indicated that the cholera strain that the travelers brought home was a particularly nasty one. V. cholerae O1, which is linked to other recent outbreaks in Eastern and Middle Africa, is resistant to a wide variety of antibiotics, namely: fluroquinolones, trimethoprim, chloramphenicol, aminoglycosides, beta-lactams, macrolides, and sulphonamides. The strain also carried a separate genetic element (a plasmid) that provided resistance mechanisms against streptomycin and spectinomycin, cephalosporins, macrolides, and sulphonamides.

The main treatment for cholera, which causes profuse watery diarrhea and vomiting, is oral rehydration. Antibiotics are sometimes used to reduce severity. Fortunately, this strain was still susceptible to the antibiotic tetracycline, one of the drugs of choice for cholera. However, there are reports of other cholera strains in Africa that have also acquired tetracycline resistance.

In all, “The extension of a cholera outbreak in Africa causing a cluster of infections in Europe is unusual,” the authors write. They call for travelers to be aware of infectious threats when eating and drinking abroad—and to not ingest holy water. Clinicians should also be aware of the potential of cholera in travelers to Ethiopia.

To truly fight cholera outbreaks, though, there needs to be sustained investment in water, sanitation, and hygiene (WASH). Cases of cholera have surged globally after the pandemic, according to the World Health Organization.

“Low-income countries will continue to need overseas development aid support to control outbreaks and epidemics using effective WASH, surveillance, communications, diagnostics and countermeasure programmatic delivery,” the authors of the Eurosurveillance report write.

Holy water brimming with cholera compels illness cluster in Europe Read More »

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FDA backpedals on RTO to stop talent hemorrhage after HHS bloodbath

drugs, fda, health, medical devices, trump administration / /

The Food and Drug Administration is reinstating telework for staff who review drugs, medical devices, and tobacco, according to reporting by the Associated Press. Review staff and supervisors are now allowed to resume telework at least two days a week, according to an internal email obtained by the AP.

The move reverses a jarring return-to-office decree by the Trump administration, which it used to spur resignations from federal employees. Now, after a wave of such resignations and a brutal round of layoffs that targeted about 3,500 staff, the move to restore some telework appears aimed at keeping the remaining talent amid fears that the agency’s review capabilities are at risk of collapse.

The cut of 3,500 staff is a loss of about 19 percent of the agency’s workforce, and staffers told the AP that lower-level employees are “pouring” out of the agency amid the Trump administration’s actions. Entire offices responsible for FDA policies and regulations have been shuttered. Most of the agency’s communication staff have been wiped out, as well as teams that support food inspectors and investigators, the AP reported.

Reviewers are critical staff with unique features. Staff who review new potential drugs, medical devices, and tobacco products are largely funded by user fees—fees that companies pay the FDA to review their products efficiently. Nearly half the FDA’s $7 billion budget comes from these fees, and 70 percent of the FDA’s drug program is funded by them.

FDA backpedals on RTO to stop talent hemorrhage after HHS bloodbath Read More »