Biology

some-dogs-can-classify-their-toys-by-function

Some dogs can classify their toys by function

animal behavior, animal cognition, Biology, Dogs, Science / /

Certain dogs can not only memorize the names of objects like their favorite toys, but they can also extend those labels to entirely new objects with a similar function, regardless of whether or not they are similar in appearance, according to a new paper published in the journal Current Biology. It’s a cognitively advanced ability known as “label extension,” and for animals to acquire it usually involves years of intensive training in captivity. But the dogs in this new study developed the ability to classify their toys by function with no formal training, merely by playing naturally with their owners.

Co-author Claudia Fugazza of Eötvös Loránd University in Budapest, Hungary, likens this ability to a person calling a hammer and a rock by the same name, or a child understanding that “cup” can describe a mug, a glass, or a tumbler, because they serve the same function. “The rock and the hammer look physically different, but they can be used for the same function,” she said. “So now it turns out that these dogs can do the same.”

Fugazza and her Hungarian colleagues have been studying canine behavior and cognition for several years. For instance, in 2023, we reported on the group’s experiments on how dogs interpret gestures, such as pointing at a specific object. A dog will interpret the gesture as a directional cue, unlike a human toddler, who will more likely focus on the object itself. It’s called spatial bias, and the team concluded that the phenomenon arises from a combination of how dogs see (visual acuity) and how they think, with “smarter” dog breeds prioritizing an object’s appearance as much as its location. This suggests the smarter dogs’ information processing is more similar to that of humans.

Another aspect of the study involved measuring the length of a dog’s head, which prior research has shown is correlated with visual acuity. The shorter a dog’s head, the more similar their visual acuity is to human vision. That’s because there is a higher concentration of retinal ganglion cells in the center of their field of vision, making vision sharper and giving such dogs binocular depth vision. The testing showed that dogs with better visual acuity, and who also scored higher on the series of cognitive tests, also exhibited less spatial bias. This suggests that canine spatial bias is not simply a sensory matter but is also influenced by how they think. “Smarter” dogs have less spatial bias.

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New pathway engineered into plants lets them suck up more CO₂

biochemistry, Biology, carbon dioxide, metabolism, photosynthesis, plants, Science / /

And, well, it worked remarkably well. The plants carrying all the genes for the McG cycle weighed two to three times as much as control plants that only had some of the genes. They had more leaves, the leaves themselves were larger, and the plants produced more seeds. In a variety of growing conditions, the plants with an intact McG cycle incorporated more carbon, and they did so without increasing their water uptake.

Having a two-carbon output also worked as expected. By feeding the plants radioactive bicarbonate, they were able to trace the carbon showing up in the expected molecules. And imaging confirmed that the plants were making so many lipids that their cells formed internal pockets containing nothing but fatty materials. Triglyceride levels increased by factors of 100 or more.

So, by a variety of measures, the plants actually did better with an extra pathway for fixing carbon. There are a number of cautions, though. For starters, it’s not clear whether what we’re learning using a small weed will also apply to larger plants or crops, or really anything much beyond Arabidopsis at the moment. It could be that having excess globs of fat floating around the cell has consequences for something like a tree. Plants grown in a lab also tend to be provided with a nutrient-rich soil, and it’s not clear whether all of this would apply to a range of real-world conditions.

Finally, we can’t say whether all the excess carbon these plants are sucking in from the atmosphere would end up being sequestered in any useful sense. It could be that all the fat would just get oxidized as soon as the plant dies. That said, there are a lot of approaches to making biofuel that rely on modifying the fats found in plants or algae. It’s possible that this can eventually help make biofuels efficient so they actually have a net positive effect on the climate.

Regardless of practical impacts, however, it’s pretty amazing that we’ve now reached the point where we can fundamentally rewire a bit of metabolism that has been in operation for billions of years without completely messing up plants.

Science, 2025. DOI: 10.1126/science.adp3528  (About DOIs).

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Nobel laureate David Baltimore dead at 87

Biology, David Baltimore, obituary, Science / /

Nobel Prize-winning molecular biologist and former Caltech president David Baltimore—who found himself at the center of controversial allegations of fraud against a co-author—has died at 87 from cancer complications. He shared the 1975 Nobel Prize in Physiology for his work upending the then-consensus that cellular information flowed only in one direction. Baltimore is survived by his wife of 57 years, biologist Alice Huang, as well as a daughter and granddaughter.

“David Baltimore’s contributions as a virologist, discerning fundamental mechanisms and applying those insights to immunology, to cancer, to AIDS, have transformed biology and medicine,” current Caltech President Thomas F. Rosenbaum said in a statement. “David’s profound influence as a mentor to generations of students and postdocs, his generosity as a colleague, his leadership of great scientific institutions, and his deep involvement in international efforts to define ethical boundaries for biological advances fill out an extraordinary intellectual life.”

Baltimore was born in New York City in 1938. His father worked in the garment industry, and his mother later became a psychologist at the New School and Sarah Lawrence. Young David was academically precocious and decided he wanted to be a scientist after spending a high school summer learning about mouse genetics at the Jackson Laboratory in Maine. He graduated from Swarthmore College and earned his PhD in biology from Rockefeller University in 1964 with a thesis on the study of viruses in animal cells. He joined the Salk Institute in San Diego, married Huang, and moved to MIT in 1982, founding the Whitehead Institute.

Baltimore initially studied viruses like polio and mengovirus that make RNA copies of the RNA genomes to replicate, but later turned his attention to retroviruses, which have enzymes that make DNA copies of viral RNA. He made a major breakthrough when he proved the existence of that viral enzyme, now known as reverse transcriptase. Previously scientists had thought that the flow of information went from DNA to RNA to protein synthesis. Baltimore showed that process could be reversed, ultimately enabling researchers to use disabled retroviruses to insert genes into human DNA to correct genetic diseases.

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a-robot-walks-on-water-thanks-to-evolution’s-solution

A robot walks on water thanks to evolution’s solution

Biology, Biomechanics, robotics, Science, water striders / /

Robots can serve pizza, crawl over alien planets, swim like octopuses and jellyfish, cosplay as humans, and even perform surgery. But can they walk on water?

Rhagobot isn’t exactly the first thing that comes to mind at the mention of a robot. Inspired by Rhagovelia water striders, semiaquatic insects also known as ripple bugs, these tiny bots can glide across rushing streams because of the robotization of an evolutionary adaptation.

Rhagovelia (as opposed to other species of water striders) have fan-like appendages toward the ends of their middle legs that passively open and close depending on how the water beneath them is moving. This is why they appear to glide effortlessly across the water’s surface. Biologist Victor Ortega-Jimenez of the University of California, Berkeley, was intrigued by how such tiny insects can accelerate and pull off rapid turns and other maneuvers, almost as if they are flying across a liquid surface.

“Rhagovelia’s fan serves as an inspiring template for developing self-morphing artificial propellers, providing insights into their biological form and function,” he said in a study recently published in Science. “Such configurations are largely unexplored in semi-aquatic robots.”

Mighty morphin’

It took Ortega-Jimenez five years to figure out how the bugs get around. While Rhagovelia leg fans were thought to morph because they were powered by muscle, he found that the appendages automatically adjusted to the surface tension and elastic forces beneath them, passively opening and closing ten times faster than it takes to blink. They expand immediately when making contact with water and change shape depending on the flow.

By covering an extensive surface area for their size and maintaining their shape when the insects move their legs, Rhagovelia fans generate a tremendous amount of propulsion. They also do double duty. Despite being rigid enough to resist deformation when extended, the fans are still flexible enough to easily collapse, adhering to the claw above to keep from getting in the animal’s way when it’s out of water. It also helps that the insects have hydrophobic legs that repel water that could otherwise weigh them down.

Ortega-Jimenez and his research team observed the leg fans using a scanning electron microscope. If they were going to create a robot based on ripple bugs, they needed to know the exact structure they were going for. After experimenting with cylindrical fans, the researchers found that Rhagovellia fans are actually structures made of many flat barbs with barbules, something which was previously unknown.

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research-roundup:-6-cool-science-stories-we-almost-missed

Research roundup: 6 cool science stories we almost missed

Biology, Science / /

DOI: Archaeometry, 2025. 10.1111/arcm.70030  (About DOIs).

DOI: Journal of Medieval History, 2025. 10.1080/03044181.2025.2546884  (About DOIs).

Snails with eyes that grow back

The golden apple snail has camera-type eyes that are fundamentally similar to the human eye. Unlike humans, the snail can regenerate a missing or damaged eye.

Credit: Alice Accorsi, UC Davis

It’s been known since at least the 18th century that some snails possess regenerative abilities, such as garden snails regrowing their heads after being decapitated. Golden apple snails can completely regrow their eyes—and those eyes share many anatomical and genetic features with human eyes, according to a paper published in the journal Nature Communications. That makes them an excellent candidate for further research in hopes of unlocking the secret to that regeneration, with the ultimate goal of restoring vision in human eyes.

Snails are often slow to breed in the lab, but golden apple snails are an invasive species and thrive in that environment, per co-author Alice Accorsi, a molecular biologist at the University of California, Davis. The snails have “camera type eyes”: a cornea, a lens to focus light, and a retina comprised of millions of photoreceptor cells. There are as many as 9000 genes that seem to be involved in regenerating an amputated eye in the snails, reducing down to 1,175 genes by the 28th day of the process, so complete maturation of the new eyes might take longer. It’s not clear whether the new eyes can still process light so the snails can actually “see,” which is a topic for further research.

Accorsi also used CRISPR/Cas9 to mutate one gene in particular (pax6) in snail embryos because it is known to control brain and eye development in humans, mice, and fruit flies. She found that apple snails with two non-functioning pax6 genes end up developing without eyes, suggesting it is also responsible for eye development in the snails. The next step is to figure out whether this gene also plays a role in the snails’ ability to regenerate their eyes, as well as other potentially involved genes.

DOI: Nature Communications, 2025. 10.1038/s41467-025-61681-6  (About DOIs).

Gorgeous glowing succulents

Succulents glow in hues of red, green, blue, and more after being infused with afterglow phosphor particles that absorb and slowly release light.

Credit: Liu et al., 2025

Perhaps you caught the launch last year of the first genetically modified glowing plant: Light Bio’s  green-hued “Firefly Petunia.” It’s not a particularly bright glow and genetic engineering is expensive, but it was nonetheless a solid step toward the long-term goal of creating glow-in-the-dark plants for sustainable lighting. Scientists at South China Agricultural University came up with a novel, cheaper approach: injecting succulents with phosphorescent chemicals akin to those used in commercial glow-in-the-dark products, aka “afterglow luminescence.” They described the work in a paper published in the journal Matter.

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genetically,-central-american-mammoths-were-weird

Genetically, Central American mammoths were weird

ancient DNA, Biology, evolution, mammoths, mexico, Science, woolly mammoth / /

This led a Mexican-European research collaboration to get interested in finding DNA from elsewhere in the Columbian mammoth’s range, which extended down into Central America. The researchers focused on the Basin of Mexico, which is well south of where any woolly mammoths were likely to be found. While the warmer terrain generally tends to degrade DNA more quickly, the team had a couple of things working in its favor. To begin with, there were a lot of bones. The Basin of Mexico has been heavily built up over the centuries, and a lot of mammoth remains have been discovered, including over 100 individuals during the construction of Mexico City’s international airport.

In addition, the team focused entirely on the mitochondrial genome. In contrast to the two sets of chromosomes in each cell, a typical cell might have hundreds of mitochondria, each of which could have dozens of copies of its genome. So, while the much smaller mitochondria don’t provide as much detail about ancestry, they’re at least likely to survive at high enough levels to provide something to work with.

And indeed they did. Altogether, the researchers obtained 61 new mitochondrial genomes from the mammoths of Mexico from the 83 samples they tested. Of these, 28 were considered high enough quality to perform an analysis.

Off on their own

By building a family tree using this genetic data, along with that from other Columbian and woolly mammoth samples, the researchers could potentially determine how different populations were related. And one thing became very clear almost immediately: They were in a very weird location on that tree.

To begin with, all of them clustered together in a single block, although there were three distinct groupings within that block. But the placement of that block within the larger family tree was notably strange. To begin with, there were woolly mammoths on either side of it, suggesting the lineage was an offshoot of woolly mammoths. That would make sense if all Columbian mammoths clustered together with the Mexican ones. But they don’t. Some Columbian mammoths from much farther north are actually more closely related to woolly mammoths than they are to the Mexican mammoths.

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new-dinosaur-species-is-the-punk-rock-version-of-an-ankylosaur

New dinosaur species is the punk rock version of an ankylosaur

ankylosaurs, Biology, dinosaurs, evolution, paleontology, Science / /

And we have known for sure that the armor was around back then, given that we’ve found the skin-derived osteoderms that comprise the armor in Jurassic deposits. But with little more than a rib and a handful of mouth parts to go on, it wasn’t really possible to say much more than that.

Until now, that is. Because the new Spicomellus remains show extremely clearly that the armor of ankylosaurs got less elaborate over time.

The small, solid-looking spikes found along the edges of later ankylosaurs? Forget those. Spicomellus had a back that was probably bristling with sharper spines, along with far larger ones along its outer edges. Each rib appears to have generated as many as six individual spikes. At a handful of locations, these spikes extended out to nearly a meter, looking more like lances than anything needed to ward off a close-in attack.

And the largest of these were along its neck. On the upper surface of its neck, several osteoderms fused to form a massive half-collar of bone and then extended out five or more individual spikes, each among the longest on the animal’s body. And there were three of these structures along the neck. “No known ankylosaur possesses any condition close to the extremely long pairs of spines on the cervical half-ring of Spicomellus,” its discoverers note.

As if its hedgehog-on-acid appearance weren’t enough, handles present on the tail vertebrae suggest that it also had a weaponized tail. All told, the researchers sum things up by saying, “The new specimen reveals extreme dermal armour modifications unlike those of any other vertebrate, extinct or extant, which fall far outside of the range of morphologies shown by other armoured dinosaurs.”

Out go the hypotheses

Because it’s so unusual, the skeleton’s characteristics are difficult to place within a neat family tree of the ankylosaurs. The researchers conclude that some details of its skeleton do suggest Spicomellus groups among the ankylosaurs and conclude that it’s probably an early branch from the main lineage. But without any other significant examples from the lineage at that time, it’s an extremely tentative conclusion. Still, the alternative is that this thing is unrelated to the only other organisms that share at least a few of its bizarre features, which is a difficult idea to swallow.

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an-inner-speech-decoder-reveals-some-mental-privacy-issues

An inner-speech decoder reveals some mental privacy issues

Biology, brain computer interface, inner speech, neurobiology, Neuroscience, Science / /

But it struggled with more complex phrases.

Pushing the frontier

Once the mental privacy safeguard was in place, the team started testing their inner speech system with cued words first. The patients sat in front of the screen that displayed a short sentence and had to imagine saying it. The performance varied, reaching 86 percent accuracy with the best performing patient and on a limited vocabulary of 50 words, but dropping to 74 percent when the vocabulary was expanded to 125,000 words.

But when the team moved on to testing if the prosthesis could decode unstructured inner speech, the limitations of the BCI became quite apparent.

The first unstructured inner speech test involved watching arrows pointing up, right, or left in a sequence on a screen. The task was to repeat that sequence after a short delay using a joystick. The expectation was that the patients would repeat sequences like “up, right, up” in their heads to memorize them—the goal was to see if the prosthesis would catch it. It kind of did, but the performance was just above chance level.

Finally, Krasa and his colleagues tried decoding more complex phrases without explicit cues. They asked the participants to think of the name of their favorite food or recall their favorite quote from a movie. “This didn’t work,” Krasa says. “What came out of the decoder was kind of gibberish.”

In its current state, Krasa thinks, the inner speech neural prosthesis is a proof of concept. “We didn’t think this would be possible, but we did it and that’s exciting! The error rates were too high, though, for someone to use it regularly,” Krasa says. He suggested the key limitation might be in hardware—the number of electrodes implanted in the brain and precision with which we can record the signal from the neurons. Inner speech representations might also be stronger in other brain regions than they are in the motor cortex.

Krasa’s team is currently involved in two projects that stemmed from the inner speech neural prosthesis. “The first is asking the question [of] how much faster an inner speech BCI would be compared to an attempted speech alternative,” Krasa says. The second one is looking at people with a condition called aphasia, where people have motor control of their mouths but are unable to produce words. “We want to assess if inner speech decoding would help them,” Krasa adds.

Cell, 2025.  DOI: 10.1016/j.cell.2025.06.015

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for-some-people,-music-doesn’t-connect-with-any-of-the-brain’s-reward-circuits

For some people, music doesn’t connect with any of the brain’s reward circuits

Biology, dopamine, music, neurobiology, reward, Science / /

“I was talking with my colleagues at a conference 10 years ago and I just casually said that everyone loves music,” recalls Josep Marco Pallarés, a neuroscientist at the University of Barcelona. But it was a statement he started to question almost immediately, given there were clinical cases in psychiatry where patients reported deriving absolutely no pleasure from listening to any kind of tunes.

So, Pallarés and his team spent the past 10 years researching the neural mechanisms behind a condition they called specific musical anhedonia: the inability to enjoy music.

The wiring behind joy

When we like something, it is usually a joint effect of circuits in our brain responsible for perception—be it perception of taste, touch, or sound—and reward circuits that give us a shot of dopamine in response to nice things we experience. For a long time, scientists attributed a lack of pleasure from things most people find enjoyable to malfunctions in one or more of those circuits.

You can’t enjoy music when the parts of the brain that process auditory stimuli don’t work properly, since you can’t hear it in the way that you would if the system were intact. You also can’t enjoy music when the reward circuit refuses to release that dopamine, even if you can hear it loud and clear. Pallarés, though, thought this traditional idea lacked a bit of explanatory power.

“When your reward circuit doesn’t work, you don’t experience enjoyment from anything, not just music,” Pallarés says. “But some people have no hearing impairments and can enjoy everything else—winning money, for example. The only thing they can’t enjoy is music.”

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mammals-that-chose-ants-and-termites-as-food-almost-never-go-back

Mammals that chose ants and termites as food almost never go back

ants, Biology, diet, evolution, mammals, Science, termintes / /

Insects are more influential than we realize

By showing that ant- and termite-based diets evolved repeatedly, the study highlights the overlooked role of social insects in shaping biodiversity. “This work gives us the first real roadmap, and what really stands out is just how powerful a selective force ants and termites have been over the last 50 million years, shaping environments and literally changing the face of entire species,” Barden said.

However, according to the study authors, we still do not have a clear picture of how much of an impact insects have had on the history of life on our planet. Lots of lineages have been reshaped by organisms with outsize biomass—and today, ants and termites have a combined biomass exceeding that of all living wild mammals, giving them a massive evolutionary influence.

However, there’s also a flip side. Eight of the 12 myrmecophagous origins are represented by just a single species, meaning most of these lineages could be vulnerable if their insect food sources decline. As Barden put it, “In some ways, specializing in ants and termites paints a species into a corner. But as long as social insects dominate the world’s biomass, these mammals may have an edge, especially as climate change seems to favor species with massive colonies, like fire ants and other invasive social insects.”

For now, the study authors plan to keep exploring how ants, termites, and other social insects have shaped life over millions of years, not through controlled lab experiments, but by continuing to use nature itself as the ultimate evolutionary archive. “Finding accurate dietary information for obscure mammals can be tedious, but each piece of data adds to our understanding of how these extraordinary diets came to be,” Vida argued.

Evolution, 2025. DOI: 10.1093/evolut/qpaf121 (About DOIs)

Rupendra Brahambhatt is an experienced journalist and filmmaker. He covers science and culture news, and for the last five years, he has been actively working with some of the most innovative news agencies, magazines, and media brands operating in different parts of the globe.

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betel-nuts-have-been-giving-people-a-buzz-for-over-4,000-years

Betel nuts have been giving people a buzz for over 4,000 years

Archeology, betel nuts, Biology, chemistry, drugs, Science, stimulants / /

Ancient rituals and customs often leave behind obvious archaeological evidence. From the impeccably preserved mummies of Egypt to psychoactive substance residue that remained at the bottom of a clay vessel for thousands of years, it seems as if some remnants of the past, even if not all are immediately visible, have defied the ravages of time.

Chewing betel nuts is a cultural practice in parts of Southeast Asia. When chewed, these reddish nuts, which are the fruit of the areca palm, release psychoactive compounds that heighten alertness and energy, promote feelings of euphoria, and help with relaxation. They are usually wrapped in betel leaves with lime paste made from powdered shells or corals, depending on the region.

Critically, the ancient teeth from betel nut chewers are distinguishable because of red staining. So when archaeologist Piyawit Moonkham, of Chiang Mai University in Thailand, unearthed 4,000-year-old skeletons from the Bronze Age burial site of Nong Ratchawat, the lack of telltale red stains appeared to indicate that the individuals they belonged to were not chewers of betel nuts.

Yet when he sampled plaque from the teeth, he found that several of the teeth from one individual contained compounds found in betel nuts. This invisible evidence could indicate teeth cleaning practices had gotten rid of the color or that there were alternate methods of consumption.

“We found that these mineralized plaque deposits preserve multiple microscopic and biomolecular indicators,” Moonkham said in a study recently published in Frontiers. “This initial research suggested the detection potential for other psychoactive plant compounds.”

Since time immemorial

Betel nut chewing has been practiced in Thailand for at least 9,000 years. During the Lanna Kingdom, which began in the 13th century, teeth stained from betel chewing were considered a sign of beauty. While the practice is fading, it is still a part of some religious ceremonies, traditional medicine, and recreational gatherings, especially among certain ethnic minorities and people living in rural areas.

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the-case-of-the-coke-snorting-chihuahua

The case of the coke-snorting Chihuahua

animals, Biology, canine behavior, Dogs, Science, veterinary medicine, veterinary science / /

Every dog owner knows that canines are natural scavengers and that vigilance is required to ensure they don’t eat toxic substances. But accidental ingestions still happen—like the chihuahua who vets discovered had somehow managed to ingest a significant quantity of cocaine, according to a case study published in the journal Frontiers in Veterinary Science.

There have been several studies investigating the bad effects cocaine can have on the cardiovascular systems of both humans and animals. However, these controlled studies are primarily done in laboratory settings and often don’t match the messier clinical realities. “Case reports are crucial in veterinary medicine by providing real-world examples,” said co-author Jake Johnson of North Carolina State University. “They capture clinical scenarios that larger studies might miss, preserve unusual presentations for future reference, and help build our collective understanding of rare presentations, ultimately improving emergency preparedness and treatment protocols.”

In the case of a male 2-year-old chihuahua, the dog presented as lethargic and unresponsive. His owners had found him with his tongue sticking out and unable to focus visually. The chihuahua was primarily an outdoor dog but was also allowed inside, and all its vaccines were up to date. Examination revealed bradycardia, i.e., a slow heart rate, a blue tinge to the dog’s mucus membranes—often a sign of too much unoxygenated hemoglobin circulating through the system—and dilated pupils. The dog’s symptoms faded after the vet administered a large dose of atropine, followed by epinephrine.

Then the dog was moved to a veterinary teaching hospital for further evaluation and testing. A urine test was positive for cocaine with traces of fentanyl, confirmed with liquid chromatography testing. The authors estimate the dog could have snorted (or ingested) as much as 96 mg of the drug. Apparently the Chihuahua had a history of ingesting things it shouldn’t, but the owners reported no prescription medications missing at home. They also did not have any controlled substances or illegal drugs like cocaine in the home.

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