anthrax

healthy-18-year-old-welder-nearly-died-of-anthrax—the-9th-such-puzzling-case

Healthy 18-year-old welder nearly died of anthrax—the 9th such puzzling case

In 2022, CDC researchers found an unexpected pattern. Since 1997, there had been seven cases of infections from Bacillus group bacteria producing the anthrax toxin—all in metalworkers. Six of the seven were welders, hence the term “welder’s anthrax,” with the remaining case in a person working in a foundry grinding metal. Of the six cases where a specific Bacillus species was identified, B. tropicus was the culprit, including in the newly reported case.

Speculating risks

It’s unclear why metalworkers, and welders specifically, are uniquely vulnerable to this infection. In their 2022 report making the connection, CDC experts speculated that it may be a combination of having weakened immune responses in the lungs after inhaling toxic metal fumes and gases created during metalwork, and having increased exposure to the deadly germs in their workplaces.

In the latest case, the teen did welding work four hours a day, four days a week, with limited ventilation, sometimes in confined spaces, and often didn’t use personal protective equipment, like a respirator. Environmental sampling of his workplace found anthrax-toxin-producing Bacillus in 28 of 254 spot samples. Other investigations of welder’s anthrax cases have found similar results.

So far, all nine cases have been detected in either Louisiana or Texas. But the experts note that cases are likely underreported, and modeling suggests these dangerous germs could be thriving in many Southern US states.

The experts also speculated that iron exposure could play a role. Bacillus bacteria need iron to live and thrive, and metalworkers can build up excess iron levels in their respiratory system during their work. Iron overload could create the perfect environment for bacterial infection. In the teen’s case, he was working with carbon steel and low-hydrogen carbon steel electrodes.

For now, the precise risk factors and why the healthy teen—and not anyone else in his workplace—fell ill remain unknown. CDC and state officials recommended changes to the workplace to protect metalworkers’ health, including better use of respirators, ventilation, and dust control.

There is also a vaccine for anthrax that’s recommended for those considered at high risk, such as certain military members, lab workers, and livestock handlers. It’s unclear if, in the future, metalworkers might also be considered in this high-risk category.

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Trump health official ousted after allegedly giving himself a fake title

Steven Hatfill, a senior advisor for the Department of Health and Human Services was fired over the weekend, with health officials telling reporters that he was terminated for giving himself a fake, inflated title and for not cooperating with leadership.

For his part, Hatfill told The New York Times that his ouster was part of “a coup to overthrow M. Kennedy,” referring to anti-vaccine Health Secretary Robert F. Kennedy Jr. Further, Hatfill said the coup was being orchestrated by Matt Buckham, Kennedy’s chief of staff, though Hatfill didn’t provide any explanation of how his ouster was evidence of that. An HHS spokesperson responded to the allegation, telling the Times that “firing a staff member for cause does not add up to a coup.”

Bloomberg was first to report Hatfill’s termination.

Background

While Hatfill was not a particularly prominent member of the Trump administration, his role—and now ouster—is notable for several reasons. Most recently, he was seen as a driving force in Kennedy’s decision to cancel $500 million in federal grants for developing mRNA vaccines against future pandemic threats. The medical and scientific communities sharply criticized the cancellations, saying they leave the country ill-prepared for the next pandemic and create a void for China or other countries to lead in scientific advances. Still, Hatfill is especially hostile to mRNA vaccine technology. In an appearance on Steve Bannon’s show in August, Hatfill falsely claimed that mRNA COVID-19 vaccines cause “biochemical havoc” on cells.

Rather than support life-saving vaccines, Hatfill embraces ineffective treatments for COVID-19, including the anti-malarial drug hydroxychloroquine and the de-worming drug ivermectin. He touted those ineffective treatments during the height of the pandemic, when he was a White House advisor during Trump’s first term.

But Hatfill might best be known for being wrongly accused of carrying out the 2001 anthrax attacks that killed five people and sickened 17. The attacks involved a strain of anthrax that was used at the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), where Hatfill had a fellowship from 1997 to 1999—though he worked on viruses while there, not bacterial diseases like anthrax. The FBI publicly announced Hatfill as a person of interest in the case in 2002. Hatfill filed a lawsuit against the Department of Justice over privacy violations, which the department settled in 2008, paying Hatfill $5.8 million. The FBI went on to accuse Bruce Ivins, another USAMRIID scientist, of carrying out the attacks. But, Ivins died by suicide in 2008 before being charged and doubts remain about the case against him.

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